H2-O Inhibits Presentation of Bacterial Superantigens, but Not Endogenous Self Antigens
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چکیده
منابع مشابه
H2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens.
H2-O/HLA-DO are MHC class II accessory molecules that modulate exogenous Ag presentation. Most class II accessory molecules are expressed in all professional APC; however, H2-O is only expressed in B cells and medullary thymic epithelial cells. Because B cells present exogenous Ags and superantigens (SAgs), and medullary thymic epithelial cells are specialized APC for self Ags during negative s...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2001
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.167.3.1371